diff --git a/fuzz/decompress.c b/fuzz/decompress.c
index a84cdac9..48eb3126 100644
--- a/fuzz/decompress.c
+++ b/fuzz/decompress.c
@@ -38,13 +38,19 @@ int LLVMFuzzerTestOneInput(const uint8_t *data, size_t size)
 {
   tjhandle handle = NULL;
   unsigned char *dstBuf = NULL;
-  int width, height, jpegSubsamp, jpegColorspace, pfi;
+  int width = 0, height = 0, jpegSubsamp, jpegColorspace, pfi;
   /* TJPF_RGB-TJPF_BGR share the same code paths, as do TJPF_RGBX-TJPF_XRGB and
      TJPF_RGBA-TJPF_ARGB.  Thus, the pixel formats below should be the minimum
      necessary to achieve full coverage. */
   enum TJPF pixelFormats[NUMPF] =
     { TJPF_RGB, TJPF_BGRX, TJPF_GRAY, TJPF_CMYK };
 
+#if defined(__has_feature) && __has_feature(memory_sanitizer)
+  /* The libjpeg-turbo SIMD extensions produce false positives with
+     MemorySanitizer. */
+  putenv("JSIMD_FORCENONE=1");
+#endif
+
   if ((handle = tjInitDecompress()) == NULL)
     goto bailout;
 
@@ -75,12 +81,12 @@ int LLVMFuzzerTestOneInput(const uint8_t *data, size_t size)
     if ((dstBuf = (unsigned char *)malloc(w * h * tjPixelSize[pf])) == NULL)
       goto bailout;
 
-    tjDecompress2(handle, data, size, dstBuf, w, 0, h, pf, flags);
-
-    /* Touch all of the output pixels in order to catch uninitialized reads
-       when using MemorySanitizer. */
-    for (i = 0; i < w * h * tjPixelSize[pf]; i++)
-      sum += dstBuf[i];
+    if (tjDecompress2(handle, data, size, dstBuf, w, 0, h, pf, flags) == 0) {
+      /* Touch all of the output pixels in order to catch uninitialized reads
+         when using MemorySanitizer. */
+      for (i = 0; i < w * h * tjPixelSize[pf]; i++)
+        sum += dstBuf[i];
+    }
 
     free(dstBuf);
     dstBuf = NULL;
diff --git a/fuzz/decompress_yuv.c b/fuzz/decompress_yuv.c
index 3fc1b898..ea9c6b85 100644
--- a/fuzz/decompress_yuv.c
+++ b/fuzz/decompress_yuv.c
@@ -38,13 +38,19 @@ int LLVMFuzzerTestOneInput(const uint8_t *data, size_t size)
 {
   tjhandle handle = NULL;
   unsigned char *dstBuf = NULL, *yuvBuf = NULL;
-  int width, height, jpegSubsamp, jpegColorspace, pfi;
+  int width = 0, height = 0, jpegSubsamp, jpegColorspace, pfi;
   /* TJPF_RGB-TJPF_BGR share the same code paths, as do TJPF_RGBX-TJPF_XRGB and
      TJPF_RGBA-TJPF_ARGB.  Thus, the pixel formats below should be the minimum
      necessary to achieve full coverage. */
   enum TJPF pixelFormats[NUMPF] =
     { TJPF_BGR, TJPF_XRGB, TJPF_GRAY };
 
+#if defined(__has_feature) && __has_feature(memory_sanitizer)
+  /* The libjpeg-turbo SIMD extensions produce false positives with
+     MemorySanitizer. */
+  putenv("JSIMD_FORCENONE=1");
+#endif
+
   if ((handle = tjInitDecompress()) == NULL)
     goto bailout;
 
@@ -75,13 +81,14 @@ int LLVMFuzzerTestOneInput(const uint8_t *data, size_t size)
          (unsigned char *)malloc(tjBufSizeYUV2(w, 1, h, jpegSubsamp))) == NULL)
       goto bailout;
 
-    tjDecompressToYUV2(handle, data, size, yuvBuf, w, 1, h, flags);
-    tjDecodeYUV(handle, yuvBuf, 1, jpegSubsamp, dstBuf, w, 0, h, pf, flags);
-
-    /* Touch all of the output pixels in order to catch uninitialized reads
-       when using MemorySanitizer. */
-    for (i = 0; i < w * h * tjPixelSize[pf]; i++)
-      sum += dstBuf[i];
+    if (tjDecompressToYUV2(handle, data, size, yuvBuf, w, 1, h, flags) == 0 &&
+        tjDecodeYUV(handle, yuvBuf, 1, jpegSubsamp, dstBuf, w, 0, h, pf,
+                    flags) == 0) {
+      /* Touch all of the output pixels in order to catch uninitialized reads
+         when using MemorySanitizer. */
+      for (i = 0; i < w * h * tjPixelSize[pf]; i++)
+        sum += dstBuf[i];
+    }
 
     free(dstBuf);
     dstBuf = NULL;
diff --git a/fuzz/transform.c b/fuzz/transform.c
index aa4673f7..2890a40f 100644
--- a/fuzz/transform.c
+++ b/fuzz/transform.c
@@ -40,9 +40,15 @@ int LLVMFuzzerTestOneInput(const uint8_t *data, size_t size)
   tjhandle handle = NULL;
   unsigned char *dstBufs[NUMXFORMS] = { NULL, NULL, NULL };
   unsigned long dstSizes[NUMXFORMS] = { 0, 0, 0 }, maxBufSize;
-  int width, height, jpegSubsamp, jpegColorspace, i, t;
+  int width = 0, height = 0, jpegSubsamp, jpegColorspace, i, t;
   tjtransform transforms[NUMXFORMS];
 
+#if defined(__has_feature) && __has_feature(memory_sanitizer)
+  /* The libjpeg-turbo SIMD extensions produce false positives with
+     MemorySanitizer. */
+  putenv("JSIMD_FORCENONE=1");
+#endif
+
   if ((handle = tjInitTransform()) == NULL)
     goto bailout;
 
@@ -73,14 +79,22 @@ int LLVMFuzzerTestOneInput(const uint8_t *data, size_t size)
   transforms[1].r.h = (height + 1) / 2;
   transforms[1].op = TJXOP_TRANSPOSE;
   transforms[1].options = TJXOPT_GRAY | TJXOPT_CROP | TJXOPT_COPYNONE;
+#if defined(__has_feature) && __has_feature(memory_sanitizer)
+  /* The libjpeg-turbo baseline Huffman encoder produces false positives with
+     MemorySanitizer. */
+  transforms[1].options |= TJXOPT_PROGRESSIVE;
+#endif
   dstBufs[1] =
     (unsigned char *)malloc(tjBufSize((width + 1) / 2, (height + 1) / 2,
-                                      jpegSubsamp));
+                                      TJSAMP_GRAY));
   if (!dstBufs[1])
     goto bailout;
 
   transforms[2].op = TJXOP_ROT90;
   transforms[2].options = TJXOPT_TRIM | TJXOPT_COPYNONE;
+#if defined(__has_feature) && __has_feature(memory_sanitizer)
+  transforms[2].options |= TJXOPT_PROGRESSIVE;
+#endif
   dstBufs[2] = (unsigned char *)malloc(tjBufSize(height, width, jpegSubsamp));
   if (!dstBufs[2])
     goto bailout;