diff --git a/forge-ai/src/main/java/forge/ai/AiProps.java b/forge-ai/src/main/java/forge/ai/AiProps.java
index fde316c8604..2808454513f 100644
--- a/forge-ai/src/main/java/forge/ai/AiProps.java
+++ b/forge-ai/src/main/java/forge/ai/AiProps.java
@@ -69,6 +69,10 @@ public enum AiProps { /** */
     ALWAYS_COUNTER_AURAS ("true"), /** */
     ALWAYS_COUNTER_SPELLS_FROM_NAMED_CARDS (""), /** */
     ACTIVELY_DESTROY_ARTS_AND_NONAURA_ENCHS ("true"), /** */
+    ACTIVELY_DESTROY_IMMEDIATELY_UNBLOCKABLE ("false"), /** */
+    DESTROY_IMMEDIATELY_UNBLOCKABLE_THRESHOLD ("2"), /** */
+    DESTROY_IMMEDIATELY_UNBLOCKABLE_ONLY_IN_DNGR ("true"), /** */
+    DESTROY_IMMEDIATELY_UNBLOCKABLE_LIFE_IN_DNGR ("5"), /** */
     PRIORITY_REDUCTION_FOR_STORM_SPELLS ("0"), /** */
     USE_BERSERK_AGGRESSIVELY ("false"), /** */
     MIN_COUNT_FOR_STORM_SPELLS ("0"), /** */
diff --git a/forge-ai/src/main/java/forge/ai/ability/DestroyAi.java b/forge-ai/src/main/java/forge/ai/ability/DestroyAi.java
index f0d6939227d..59f427e49d4 100644
--- a/forge-ai/src/main/java/forge/ai/ability/DestroyAi.java
+++ b/forge-ai/src/main/java/forge/ai/ability/DestroyAi.java
@@ -5,6 +5,7 @@ import forge.ai.*;
 import forge.game.ability.AbilityUtils;
 import forge.game.ability.ApiType;
 import forge.game.card.*;
+import forge.game.combat.CombatUtil;
 import forge.game.cost.Cost;
 import forge.game.cost.CostPart;
 import forge.game.cost.CostSacrifice;
@@ -115,6 +116,9 @@ public class DestroyAi extends SpellAbilityAi {
                 }
             }
             list = CardLists.getNotKeyword(list, "Indestructible");
+            if (CardLists.getNotType(list, "Creature").isEmpty()) {
+                list = prioritizeCreaturesWorthDestroyingNow(ai, list);
+            }
             if (!SpellAbilityAi.playReusable(ai, sa)) {
                 list = CardLists.filter(list, new Predicate<Card>() {
                     @Override
@@ -291,6 +295,9 @@ public class DestroyAi extends SpellAbilityAi {
 
             CardCollection preferred = CardLists.getNotKeyword(list, "Indestructible");
             preferred = CardLists.filterControlledBy(preferred, ai.getOpponents());
+            if (CardLists.getNotType(preferred, "Creature").isEmpty()) {
+                preferred = prioritizeCreaturesWorthDestroyingNow(ai, preferred);
+            }
 
             // If NoRegen is not set, filter out creatures that have a
             // regeneration shield
@@ -444,4 +451,51 @@ public class DestroyAi extends SpellAbilityAi {
             return tempoCheck;
         }
     }
+
+    public static CardCollection prioritizeCreaturesWorthDestroyingNow(final Player ai, final CardCollection oppCards) {
+        if (!CardLists.getNotType(oppCards, "Creature").isEmpty()) {
+            // non-creatures were passed, nothing to do here
+            return oppCards;
+        }
+
+        boolean enablePriorityRemoval = false;
+        boolean priorityRemovalOnlyInDanger = false;
+        int priorityRemovalThreshold = 0;
+        int lifeInDanger = 5;
+        if (ai.getController().isAI()) {
+            AiController aic = ((PlayerControllerAi)ai.getController()).getAi();
+            enablePriorityRemoval = aic.getBooleanProperty(AiProps.ACTIVELY_DESTROY_IMMEDIATELY_UNBLOCKABLE);
+            priorityRemovalThreshold = aic.getIntProperty(AiProps.DESTROY_IMMEDIATELY_UNBLOCKABLE_THRESHOLD);
+            priorityRemovalOnlyInDanger = aic.getBooleanProperty(AiProps.DESTROY_IMMEDIATELY_UNBLOCKABLE_ONLY_IN_DNGR);
+            lifeInDanger = aic.getIntProperty(AiProps.DESTROY_IMMEDIATELY_UNBLOCKABLE_LIFE_IN_DNGR);
+        }
+
+        if (!enablePriorityRemoval) {
+            // Nothing to do here, the profile does not allow prioritizing
+            return oppCards;
+        }
+
+        CardCollection aiCreats = CardLists.filter(ai.getCardsIn(ZoneType.Battlefield), CardPredicates.Presets.CREATURES);
+
+        CardCollection priorityCards = new CardCollection();
+        for (Card atk : oppCards) {
+            if (ComputerUtilCard.isUselessCreature(atk.getController(), atk)) {
+                continue;
+            }
+            for (Card blk : aiCreats) {
+                if (!CombatUtil.canBlock(atk, blk, true)) {
+                    boolean threat = atk.getNetCombatDamage() >= ai.getLife() - lifeInDanger;
+                    if (!priorityRemovalOnlyInDanger || threat) {
+                        priorityCards.add(atk);
+                    }
+                }
+            }
+        }
+
+        if (!priorityCards.isEmpty() && priorityCards.size() <= priorityRemovalThreshold) {
+            return priorityCards;
+        }
+
+        return oppCards;
+    }
 }
diff --git a/forge-gui/res/ai/Cautious.ai b/forge-gui/res/ai/Cautious.ai
index d1a0da2613d..7985486efeb 100644
--- a/forge-gui/res/ai/Cautious.ai
+++ b/forge-gui/res/ai/Cautious.ai
@@ -91,6 +91,18 @@ RESERVE_MANA_FOR_MAIN2_CHANCE=100
 # If enabled, the AI will target artifacts and non-aura enchantments with removal aggressively
 ACTIVELY_DESTROY_ARTS_AND_NONAURA_ENCHS=true
 
+# If enabled, the AI will prioritize removing creatures that it can't block at all (e.g. Flying in absence of flying
+# blockers). This is a master toggle. If disabled, the following three options do nothing.
+ACTIVELY_DESTROY_IMMEDIATELY_UNBLOCKABLE=false
+# How many unblockable creatures can there be when the AI should still consider prioritizing something (when there are
+# too many, probably it's just worth going for the biggest threat overall instead)
+DESTROY_IMMEDIATELY_UNBLOCKABLE_THRESHOLD=2
+# Only consider prioritizing the destruction of immediately unblockable creatures if life is in danger
+DESTROY_IMMEDIATELY_UNBLOCKABLE_ONLY_IN_DNGR=true
+# How much life can there remain after a swing of the immediately unblockable creature for it to be considered dangerous
+# for the purpose of previous option
+DESTROY_IMMEDIATELY_UNBLOCKABLE_LIFE_IN_DNGR=5
+
 # Permission timings
 MIN_SPELL_CMC_TO_COUNTER=2
 CHANCE_TO_COUNTER_CMC_1=0
diff --git a/forge-gui/res/ai/Default.ai b/forge-gui/res/ai/Default.ai
index 28ea9b09e5e..e8fd3709b3a 100644
--- a/forge-gui/res/ai/Default.ai
+++ b/forge-gui/res/ai/Default.ai
@@ -91,6 +91,18 @@ RESERVE_MANA_FOR_MAIN2_CHANCE=100
 # If enabled, the AI will target artifacts and non-aura enchantments with removal aggressively
 ACTIVELY_DESTROY_ARTS_AND_NONAURA_ENCHS=true
 
+# If enabled, the AI will prioritize removing creatures that it can't block at all (e.g. Flying in absence of flying
+# blockers). This is a master toggle. If disabled, the following three options do nothing.
+ACTIVELY_DESTROY_IMMEDIATELY_UNBLOCKABLE=false
+# How many unblockable creatures can there be when the AI should still consider prioritizing something (when there are
+# too many, probably it's just worth going for the biggest threat overall instead)
+DESTROY_IMMEDIATELY_UNBLOCKABLE_THRESHOLD=2
+# Only consider prioritizing the destruction of immediately unblockable creatures if life is in danger
+DESTROY_IMMEDIATELY_UNBLOCKABLE_ONLY_IN_DNGR=true
+# How much life can there remain after a swing of the immediately unblockable creature for it to be considered dangerous
+# for the purpose of previous option
+DESTROY_IMMEDIATELY_UNBLOCKABLE_LIFE_IN_DNGR=5
+
 # Permission timings
 MIN_SPELL_CMC_TO_COUNTER=0
 CHANCE_TO_COUNTER_CMC_1=30
diff --git a/forge-gui/res/ai/Experimental.ai b/forge-gui/res/ai/Experimental.ai
index e54bb925384..17863cf0729 100644
--- a/forge-gui/res/ai/Experimental.ai
+++ b/forge-gui/res/ai/Experimental.ai
@@ -29,7 +29,7 @@ USE_BERSERK_AGGRESSIVELY=true
 TRY_TO_HOLD_COMBAT_TRICKS_UNTIL_BLOCK=true
 # Chance to hold combat tricks until blockers are declared. If -1 is specified, this chance is not used, and the standard
 # evaluation for offensive pump buff is used instead.
-CHANCE_TO_HOLD_COMBAT_TRICKS_UNTIL_BLOCK=65
+CHANCE_TO_HOLD_COMBAT_TRICKS_UNTIL_BLOCK=75
 
 # Trade blocking preferences (enabling these will make the AI trade more aggressively when considering blocks,
 # but only with creatures that are worse in abilities and have lower or the same power as the attacker). Note
@@ -91,6 +91,18 @@ RESERVE_MANA_FOR_MAIN2_CHANCE=100
 # If enabled, the AI will target artifacts and non-aura enchantments with removal aggressively
 ACTIVELY_DESTROY_ARTS_AND_NONAURA_ENCHS=true
 
+# If enabled, the AI will prioritize removing creatures that it can't block at all (e.g. Flying in absence of flying
+# blockers). This is a master toggle. If disabled, the following three options do nothing.
+ACTIVELY_DESTROY_IMMEDIATELY_UNBLOCKABLE=true
+# How many unblockable creatures can there be when the AI should still consider prioritizing something (when there are
+# too many, probably it's just worth going for the biggest threat overall instead)
+DESTROY_IMMEDIATELY_UNBLOCKABLE_THRESHOLD=3
+# Only consider prioritizing the destruction of immediately unblockable creatures if life is in danger
+DESTROY_IMMEDIATELY_UNBLOCKABLE_ONLY_IN_DNGR=false
+# How much life can there remain after a swing of the immediately unblockable creature for it to be considered dangerous
+# for the purpose of previous option
+DESTROY_IMMEDIATELY_UNBLOCKABLE_LIFE_IN_DNGR=5
+
 # Permission timings
 MIN_SPELL_CMC_TO_COUNTER=2
 CHANCE_TO_COUNTER_CMC_1=30
diff --git a/forge-gui/res/ai/Reckless.ai b/forge-gui/res/ai/Reckless.ai
index 6bb65394dcd..e6958bf21e0 100644
--- a/forge-gui/res/ai/Reckless.ai
+++ b/forge-gui/res/ai/Reckless.ai
@@ -91,6 +91,18 @@ RESERVE_MANA_FOR_MAIN2_CHANCE=100
 # If enabled, the AI will target artifacts and non-aura enchantments with removal aggressively
 ACTIVELY_DESTROY_ARTS_AND_NONAURA_ENCHS=true
 
+# If enabled, the AI will prioritize removing creatures that it can't block at all (e.g. Flying in absence of flying
+# blockers). This is a master toggle. If disabled, the following three options do nothing.
+ACTIVELY_DESTROY_IMMEDIATELY_UNBLOCKABLE=false
+# How many unblockable creatures can there be when the AI should still consider prioritizing something (when there are
+# too many, probably it's just worth going for the biggest threat overall instead)
+DESTROY_IMMEDIATELY_UNBLOCKABLE_THRESHOLD=2
+# Only consider prioritizing the destruction of immediately unblockable creatures if life is in danger
+DESTROY_IMMEDIATELY_UNBLOCKABLE_ONLY_IN_DNGR=true
+# How much life can there remain after a swing of the immediately unblockable creature for it to be considered dangerous
+# for the purpose of previous option
+DESTROY_IMMEDIATELY_UNBLOCKABLE_LIFE_IN_DNGR=5
+
 # Permission timings
 MIN_SPELL_CMC_TO_COUNTER=0
 CHANCE_TO_COUNTER_CMC_1=80